Theory and Defination : The Barton–McCombie de-oxygenation is an organic reaction in which an hydroxy functional group in an organic compound is replaced by a hydride to give an alkyl group. It is named for the British chemists Sir Derek Harold Richard Barton (1918–1998) and Stuart W. McCombie. General Reactio…

Theory and Defination : Barton Decarboxylation is the organic reaction in which the conversion of a carboxylic acid to a thiohydroxamate ester followed by heating the product in the presence of a suitable hydrogen donor such as tri-n-butylin hydride, produces a reductive decarboxylation. This sequence of reactio…